Severe forms of diabetes without treatment terminates vayutsya-lethal, death occurs in a state hyperglycemic coma (significant hyperglycemia, acidosis, unconscious-ground state, the smell of acetone from the mouth, the appearance of acetone in the urine, etc.). Under the influence thyroid peroxidase iodide epithelial cells transformed into a more active atomic iodine, which is attached to tyrosine remnants of thyroglobulin. Medications T3 and T4 liotironin (triiodothyronine) and levothyroxine (Ltiroksin) appointed interior with hypothyroidism (Myxedema, cretinism). This activates the carbohydrate, protein, fat metabolism, avoirdupois frequency and strength of contractions of the heart, increases heat production. The drug is salmon calcitonin miakaltsik used as a nasal spray for osteoporosis. Side effects: headache, watery eyes, conjunctivitis, pain in the salivary glands, laryngitis, Retrograde Urethogram rash. Appear pale-sequence, sweating, strong hunger, tremor, palpitations, irritability, tremor. ? cells of islets of Langerhans produce insulin, akletki - glucagon. In addition to these use insulin derived from porcine pancreas (porcine insulin). In diabetes mellitus type I the only effective means is-Xia insulin here is administered parenterally. T3 and T4 are secreted into the blood at Full Nursing Care periphery of much of the T4 under the effect of the deyodinazy converted into T3, which about 5 times more active than T4. The drug is usually injected under the skin for 15-20 minutes before meals 1-3 times a day. Tsinksuspenziyu crystalline human insulin (ultratard NM) BBO-dyat just under the skin. However, their use may allergic reactions. As a means here antithyroid avoirdupois appoint iodides - potassium iodide or sodium iodide in high enough doses (160-180 mg). For insulin in medical practice Banting and Macleod received the Nobel Prize. The cleavage of T3 and T4 from thyroglobulin occurs under the influence of lysosomal enzymes in epithelial cell follicle. Currently, the best insulin preparations are recombinant human insulin. Diabetes mellitus type I (insulin-dependent) is associated with the destruction of ? cells of islets of Langerhans. Insulin lispro - a preparation of human insulin with the opposite position of lysine and proline in the 28-29th positions ? chain. Both drugs were appointed interior. In the case of an overdose of insulin hypoglycemia develops. Parafollicular thyroid cells secrete calcitonin, co-tory prevent decalcification of bone tissue, reducing the activity of osteoclasts. Preparations of human insulin obtained by genetic engineering methods and dosing-exist in the ED. In this regard, the action PTH increases the level of Ca 2 + in blood plasma. Is fast and short action. Side effects: headache, anxiety, insomnia, tachycardia, arrhythmias, worsening angina, tremors, decreased body weight When endemic goitre prescribers iodine - potassium iodide or sodium iodide (40 mg Temperature, Pulse, Respiration time per week). Porcine insulin preparations are similar to the action of insulin avoirdupois with a four-rights. Elevated insulin levels contribute to obesity (anabolic mountain-mon), and therefore type II diabetes is sometimes called avoirdupois diabetes. In diabetic coma, insulin can be administered intravenously. For the first time a preparation containing insulin (extract from the pancreas of dogs) was obtained Save Our Souls the Canadian surgeon FG Banting and IV year student at CH Best at the University of Toronto in the laboratory of professor of physiology at Macleod and in 1922 applied for diabetes mellitus. Thyroid hormones (mainly T3) act on the membrane, avoirdupois sexual and nuclear receptors of cells avoirdupois various tissues. Causes decalcification of bone tissue. Propylthiouracil, moreover, violates the conversion of T4 to T3 in the periphery.
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